麻豆视频

夏欣一博士
主任医师
电话：邮箱：xinyixia@madousp8.net 地址：江苏省南京市玄武区中山东路305号研究方向：

重大疾病诊断标志物及发病机制；检验医学新技术新方法
  • 个人简介
  • 学术兼职
  • 代表性论文
  • 承担科研项目
  • 获奖情况

东部战区总医院（麻豆视频 附属金陵医院）检验科副主任，主任医师、教授、博士生导师，麻豆视频 生命分析化学全国重点实验室固定成员。曾任武汉火神山医院检验科主任，入选香江学者计划、江苏省333高层次人才工程（第二层次）、江苏省医学重点人才、军区334高层次人才、军队优秀专业技术人才岗位津贴（二类），兼任中国医药生物技术协会生物诊断分会委员、江苏省医学会检验分会常委兼分子组长、江苏省医师协会检验分会委员、南京医学会检验分会副主委、《临床检验杂志》常务编委等。主持国家自然科学基金、省自然科学基金、省重点研发计划等课题20余项；以第一/通讯作者发表论文60余篇，主要发表于Blood、Nat Commun、Cell Discov等权威期刊，入选ESI高被引3篇；获中国妇幼科技成果一等奖、军队科技进步二等奖、江苏省医学新技术一等奖等成果8项。获评全国白求恩式检验人，带领团队获抗击新冠肺炎疫情全国表彰。欢迎青年学子来本团队攻读博、硕士学位或从事博士后研究。


中国医药生物技术协会生物诊断分会委员

江苏省医学会检验分会常委兼分子组长

江苏省医师协会检验分会委员

南京医学会检验分会副主委

《临床检验杂志》常务编委

1. Zhou H, Xu Z, Jiang C, Wu Q, Zhang C, Liu Z, Zhang X, Li W, Pang Y, Zhang J, Pan W, Chen M, Xia X. Ionizing radiation-induced  disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction. Cell Commun Signal. 2025;23(1):58.

2. Yang Y, Wu Q, Liu X, Zhou H, Lei J, Luo L, Xia X. SARS-CoV-2-encoded miR-nsp3-3p promotes pulmonary fibrosis by inhibiting expression of ALCAM. Virol Sin. 2025 Aug;40(4):560-570.

3.  Sun N, Zhang J, Guo W, Cao J, Chen Y, Gao D, Xia X.Comparative analysis of metagenomic next-generation sequencing for pathogenic identification in clinical body fluid samples.BMC Microbiol. 2025 Mar 25;25(1):165.

4.  Liu Y, Yin S, Chen S, Zhang C, Lubanga N, Tai P, Xiong M, Fan B, Yang X, Xia X, Hou P, He B. Rapid detection of Helicobacter pylori and its virulence genes by fluorescence-chromogenic double-indicator LAMP (FC-LAMP).Clin Chim Acta. 2025 Oct 15;580:120667.

5.  Wu W, Song J, Wu Q, Wu X, Sun N, Xia X. Development and evaluation of CD45-conjugated magnetic particles-based host cell depletion for enhanced metagenomic next-generation sequencing in bloodstream infection.J Chromatogr B Analyt Technol Biomed Life Sci. 2025 Dec 15;1267:124823.

6.  Dai W, Wu J, Shui Y, Wu Q, Wang J, Xia X. NF-κB-activated oncogene inhibition strategy for cancer gene therapy.Cancer Gene Ther. 2024 Nov;31(11):1632-1645.

7.  Gao Y, Chen X, Zhu Y, Zhou S, Zhang L, Wu Q, Zhang H, Wang Z, Chen X, Xia X, Pu L, Wang X. Establishment of two novel organoid lines from patients with combined hepatocellular cholangiocarcinoma. Hum Cell. 2024 Dec 6;38(1):27.

8.  Qin S, Yao X, Li W, Wang C, Xu W, Gan Z, Yang Y, Zhong A, Wang B, He Z, Wu J, Wu Q, Jiang W, Han Y, Wang F, Wang Z, Ke Y, Zhao J, Gao J, Qu L, Jin P, Guan M, Xia X, Bian X. Novel insight into the underlying dysregulation mechanisms of immune cell-to-cell ommunication by analyzing multitissue single-cell atlas of two COVID-19 patients. Cell Death Dis. 2023 Apr 22;14(4):286.3.

9.  Shen J, Wu Q, You J, Zhang X, Zhu L, Xia X, Xue C, Tian X. Characterization of a Novel Gja8 (Cx50) Mutation in a New Cataract Rat Model.Invest Ophthalmol Vis Sci. 2023 Jun 1;64(7):18.

10.  Dai W, Zhong A, Qiao Q, Wu J, Li W, Wu Q, Zhou H, Qin S, Jiang W, Zhang J, Xia X. Characteristics of lymphocyte subset alterations in COVID-19 patients with different levels of disease severity.Virol J. 2022 Nov 19;19(1):192.

11.  Wang C, Qin S, Pan W, Shi X, Gao H, Jin P, Xia X, Ma F. mRNAsi-related genes can effectively distinguish hepatocellular carcinoma into new molecular subtypes. Comput Struct Biotechnol J. 2022 Jun 8;20:2928-2941.

12.  Li Y, Ke Y, Xia X, Wang Y, Cheng F, Liu X, Jin X, Li B, Xie C, Liu S, Chen W, Yang C, Niu Y, Jia R, Chen Y, Liu X, Wang Z, Zheng F, Jin Y, Li Z, Yang N, Cao P, Chen H, Ping J, He F, Wang C, Zhou G. Genome-wide association study of COVID-19 severity among the Chinese population.Cell Discov. 2021 Aug 31;7(1):76.

13.  Fu Z, Wang J, Wang Z, Sun Y, Wu Y, Zhang Y, Liu X, Zhou Z, Zhou L, Zhang C, Yi Y, Xia X, Wang L, Xi Chen. A virus-derived microRNA-like small RNA serves as aserum biomarker to prioritize the COVID-19 patients at high risk of developing severe disease. Cell Discov, 2021, 7,48. 

14.  Liu S, Wu J, Xia Q, Liu H, Li W, Xia X, Wang J.Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learning.Comput Struct Biotechnol J. 2020 Jul 7;18:1891-1903.

15.  Qin S, Xu W, Wang C, Jiang S, Dai W, Yang Y, Shen J, Jin P, Ma F, Xia X. Analyzing master regulators and scRNA-seq of COVID-19 patients reveals an underlying anti-SARS-CoV-2 mechanism of ZNF proteins. Brief Bioinform, 2021,Sep 2;22(5) 

16.  Xu X, Luo T, Gao J, Lin N, Li W, Xia X, Wang J.CRISPR-Assisted DNA Detection: A Novel dCas9-Based DNA Detection Technique.CRISPR J. 2020 Dec;3(6):487-502.

17.  Xia X, Li K, Wu L, Wang Z, Zhu M, Huang B, Li J, Wang Z, Wu W, Wu M, Li W, Li L, Cai Y, Bosco B, Zhong A, Liu X, Lv T, Gan Z, Chen G, Pan Y, Liu C, Zhang K, Xu X, Wang C, Wang Q. Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion. Blood, 2020, 136(6):755-759.

18.  Li K, Huang B, Wu M, Zhong A, Li L, Cai Y, Wang Z, Wu L, Zhu M, Li J, Wang Z, Wu W, Li W, Bosco B, Gan Z, Qiao Q, Wu J, Wang Q, Wang S, Xia X. Dynamic changesinanti-SARS-CoV-2 antibodies during SARS-CoV-2 infection and recovery from COVID-19.Nat Commun, 2020, 11(1):6044.

19.  Chen X, Xu M, Xu X, Zeng K, Liu X, Sun L, Pan B, He B, Pan Y, Sun H, Xia X, Wang S. METTL14 suppresses CRC progression via regulating N6-ethyladenosine-dependent primary miR-375 processing. Mol Ther. 2020, (2):599-612.

20.  Ye M, Fu D, Ren Y, Wang F, Wang D, Zhang F, Xia X, Lv T. Treatment with convalescent plasma for COVID-19 patients in Wuhan, China. J Med Virol. 2020, 92(10):1890-1901.




1.国家自然科学基金面上项目，2024,在研，主持；

2.江苏省自然科学基金面上项目，2024，在研，主持；

3.麻豆视频 金陵医院创新重大项目，2023，在研，主持；

4.江苏省重点研发计划，2018，结题，主持；

中国妇幼健康科学技术奖成果三等奖（2025，第一完成人）

江苏省医学新技术引进二等奖（2021，第一完成人）

中国妇幼健康科学技术奖一等奖（2019，第二完成人）

江苏省科学技术奖三等奖（2012，第三完成人）

军队医疗成果二等奖（2010，第三完成人）

江苏省医学新技术引进一等奖（2010，第二完成人）